Wolbachia: Why These Bacteria Are Important to Genome Research

Wolbachia: why these bacteria are important to genome research.

What's in a name? Why these proteins are intrinsically disordered: Why these proteins are intrinsically disordered.

"What's in a name? That which we call a rose By any other name would smell as sweet." From "Romeo and Juliet", William Shakespeare (1594) This article opens a series of publications on disambiguation of the basic terms used in the field of intrinsically disordered proteins. We start from the beginning, namely from the explanation of what the expression "intrinsically disordered protein" actuall...

Why are wordnets important?

Wordnets are lexical databases in which words are organized into clusters based on their meanings, and they are linked to each other through different semantic and lexical relations. The first wordnet called the Princeton WordNet was created for English, which were followed by various wordnets created within the framework of the EuroWordNet and BalkaNet projects, among others. Here we focus on ...

Why are bacteria refractory to antimicrobials?

The incidence of antibiotic resistance in pathogenic bacteria is rising. Antibiotic resistance can be achieved via three distinct routes: inactivation of the drug, modification of the target of action, and reduction in the concentration of drug that reaches the target. It has long been recognized that specific antibiotic resistance mechanisms can be acquired through mutation of the bacterial ge...

Why Initial Conditions Are Important

Most simulation textbooks assume that a model can be started in an empty state and the final output will not be affected, so long as the “warm-up period” is excluded from the analysis. In this paper we test this assumption, using a discrete-event model of a existing manufacturing facility. Using a series of model runs with no initial Work in Progress (WIP) and another series of simulation runs ...